Vitamin B12 Cyanocobalmin Labpedia Net In this test, vitamin b12 is radiolabeled with 57 ′ co or 58 ′ co vitamin b12 is given. an oral dose of 0.5 to 1.0 µg radiolabelled vitamin b12 is given. within 2 hours, the patient is injected with a flushing dose of 1000 µg of unlabelled vitamin b12. radioactivity is measured in the urine, feces, and serum. Definition. this is megaloblastic anemia due to deficiency of vitamin b12, because of malabsorption, which is believed as an autoimmune phenomenon to gastric parietal cells and their products. parietal cells are the source of intrinsic factor. this intrinsic factor binds the b12 and allows its absorption in the ileum.
Vitamin B12 Cyanocobalmin Labpedia Net Vitamin b12 serum level is reduced where the normal values are 160 to 925 ng dl. vitamin b12 level in the rbcs is also decreased; the normal value is 72 to 512 ng dl. serum folate level is also decreased in folic acid deficiency, where the normal value is 10 to 15 µg l. rbc folate is also reduced and may be very low. the normal value is 300. The increase in nucleic acid degradation produced by admin vitamin b12 to vitamin b12 deficient patients could result in gout in susceptible individuals. therapeutic response to vitamin b12 may be impaired by concurrent infection, uremia, folic acid or iron deficiency, or by drugs having bone marrow suppressant effects. The recommended daily amount of vitamin b 12 for adults is 2.4 micrograms (mcg). most people can get enough vitamin b 12 in the foods they eat. but people who follow a vegetarian or vegan diet should eat nutritional yeast and other foods fortified with vitamin b 12. or they can take a low dose multivitamin that includes 2.4 mcg of vitamin b 12. Introduction. vitamin b12 is a water soluble vitamin that is naturally present in some foods, added to others, and available as a dietary supplement and a prescription medication. because vitamin b12 contains the mineral cobalt, compounds with vitamin b12 activity are collectively called cobalamins [1].
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